Author Name: Farzad Deyhim
Cardiovascular disease is attributed to sedentary lifestyle, diets high in fat and refined carbohydrates, and low in fruits and vegetables. The objective of this study was to determine whether drinking grapefruit juice positively influences cardiovascular risk markers, antioxidant status, and lipid peroxidation in adults not changing their eating habits. An experiment to test whether daily consumption of 20 fl. oz. of freshly squeezed grapefruit juice for two months affected lipid panels, C-reactive protein, insulin, body composition, blood pressure, antioxidant status, and malondialdehyde production was conducted. Fasting blood samples were collected pre-treatment and 60 days after drinking grapefruit juice post-treatment. Drinking grapefruit juice did not affect (P > 0.1) plasma total cholesterol, triglycerides, Apo A, Apo B, LDL, HDL, body fat percentage, BMI, blood pressure, plasma insulin, or C-reactive protein. Drinking grapefruit juice did not affect systolic and diastolic blood pressure. However, drinking grapefruit juice significantly (P < 0.05) increased total plasma antioxidant capacity and decreased (P < 0.05) plasma malondialdehyde concentration. Drinking grapefruit juice may be cardio-protective via increasing total antioxidant status and decreasing lipid peroxidation independent of any of the cardiovascular risk markers measured in the study.
Basics of Dermal Fillers praise
Author: Beomjoon Kim
Background: Department of Dermatology, Chung-Ang University College of Medicine, Seoul, South Korea
For more infomation Please go through this URL: https://www.ommegaonline.org/article-details/Basics-of-Dermal-Fillers/628
Currently, soft tissue augmentation with fillers is widely accepted as a treatment that can improve quality of life. Fillers are prepared from diverse materials including autologous implants, collagens, hyaluronic acid (HA), and biosynthetic polymers, and are marketed for cosmetic purposes. Among these fillers, HA fillers are the most popular because of their volumizing effect, biocompatibility, and easy correction after treatment.
Naturally occurring HA is a glycosaminoglycan uniformly present throughout all living species in connective tissue, vitreous humor, synovium, and the dermis. HA is a polysaccharide composed of the disaccharide units of D-glucuronic acid and N-acetyl-D-glucosamine with β(1→4) glycosidic linkages. HA is major component of connective tissues, especially the human dermis. However, natural HA is rapidly degraded by enzymes and radicals that are present in the body. The half life of HA in human tissues generally ranges from 1 to 2 days, therefore, treating defects such as wrinkles by injection of free HA into skin is effective for less than a week. Despite the excellent biocompatibility of HA, its time-dependent degradation is a serious drawback. To overcome the lack of persistence of free HA, HA-based dermal fillers are produced by chemical modification, namely cross linking. HA can be cross linked by using diverse cross-linking reagents such as 1,4-butanediol diglycidyl ether (BDDE), divinyl sulfone (DVS), or diazomethane.
Author: Nadia Mulinacci
Pomegranate peel (exocarp and mesocarp), which constitutes about 50% of the whole fresh fruit, is extensively used in folk medicine but discarded in large quantities as by-product, after the juice production. The objective was to valorize this by-product derived from Laffan and Wonderful varieties, by improving the knowledge on its composition and by applying sustainable extraction processes.
The extraction was performed separately on exocarp and mesocarp, using water at different temperatures, and 70% ethanol; the ellagitannins were determined by HPLC-DAD and MS- TOF. The polysaccharide fraction was extracted and determined by weight (yields). The profiles of mesocarp and exocarp separately of the two varieties were very similar and characterized by the same ellagitannins (ETs) of pomegranate juice. The highest ETs amount was obtained from mesocarp (140 - 150 mg/dried matter) via decoction and hydroalcoholic extraction. No ETs degradation was observed during decoction, α and β punicalagins were always 59 – 78 % of the total ETs. Decoction as a green process easy to apply can help to valorize these by-products as it is able to recover polysaccharides as well as ellagitannins. A Nutritional label was prepared for the whole dry decoction from Wonderful mesocarp.
Author: Maria Nardoia
The effect of 2% grape seed and 2% grape skin powder added to chicken thigh patties stored at 4°C was assessed by measuring lipid oxidation, total phenolic content, pH, color changes and sensory attributes. The addition of these grape by-products to the patties lowered pH values and significantly reduced in lightness, redness and yellowness compared with the control. However, the addition of grape seed and skin significantly improved the oxidative stability of raw chicken patties due to higher total phenolic content, grape seed being more effective than skin in this regard. The phenolic content of these samples remained stable even after cooking. The acceptability of the chicken meat in general was not affected by the addition of grape by-products. These results show that grape seed and grape skin could potentially be used as natural antioxidants in raw chicken patties and would be accepted by consumers.
Author:Antonia Yordanova Atanassova.
Clinic of Gastroenterology, University Hospital “St. Marina”, Medical University of Varna
Desmoid tumors are benign neoplasms, but are often unresectable because of their aggressive and local infiltration, compression of surrounding structures and massive involvement of adjacent vital structures. Our aim is to increase awareness of this condition so that clinicians will consider diagnosing it. This will facilitate prompt diagnosis and treatment. This is a case of a 43 year old woman with medical history of Berger`s disease, immunosuppressive therapy, a kidney transplant and sporadic mesenteric desmoid tumors appearing after solid organ transplantation. Eighteen months after the removal of the tumors, she was diagnosed with essential thrombocytosis. No evidences of recurrence after operation.
Author Name: Pesona Grace Lucksom
Department of Obstetrics and Gynecology, Sikkim Manipal Institute of Medical, Sikkim, India
For more information Please go through this URL: https://www.ommegaonline.org/article-details/Reaching-adolescents-through-Sex-education-where-do-we-stand/1078
Adolescence is a period between 10 - 19 years of age as described by World Health Organization(WHO). This is a period when there is rapid physical, psychological and sexual maturity. Sex education refers to a broad program designed to impart knowledge/training regarding values, attitudes and practices affecting family relationships. Sex education in children increases awareness about the biological and physiological changes occurring in their bodies and help them become comfortable with it and not conscious about it. Failure to understand that ‘sex education’ is different from ‘sex literature’ is the main obstacle for imparting knowledge among the youngsters. We feel proud of epics such as ‘Kamasutra’ but Kamasutra doesn’t talk about Human Immunodeficiency Virus / sexually transmitted infection (HIV/STI). In the absence of right guidance and information at this stage they are more likely to have multi-partner unprotected sex with high risk behavior groups. Sex education has been considered an important issue in the developed countries where it is incorporated as a part of school education however in many places such as Tanzania, Australia, India etc., it is considered a social taboo.
Author: Enrico Doria
Fruit and vegetables wastes not only have no commercial value, but also require expensive operations of removal and disposal, representing a significant cost for the manufacturers of plant products. However, this material may represent an important resource of commercially worth phyto-molecules endowed with various nutraceutical properties. In the present work, we have verified the possibility of using fruit and vegetable waste materials as a source of bioactive compounds. Several nutraceutical compounds of high economic interest were extracted and quantified from various waste plant materials deriving from the production phase (“first-gamma products”) or discarded during the preparation of fresh ready-to-cook or ready-to-eat packaged products (“fourth-gamma products”). Obtained results showed that, despite the precarious and uncontrolled conditions which plant wastes products are subjected, the levels of the examined bioactive compounds are present in relevant amount, also in the parts of the plant that are discarded during the preparation of the ready-to-eat/cook products.
Author: Tetsuo Nishikawa
Liraglutide (Victoza, Novo Nordisk Pharma Ltd.), a GLP-1 analogue preparation for diabetes mellitus has been reported to potently reduce the blood sugar level and decrease the body weight when injected once a day. As the risk of hypoglycemia is low, it has been used as an epoch-making drug in a rapidly increasing number of patients. In this study, we investigated the effects of liraglutide subcutaneously injected once a day in 48 patients with type 2 diabetes who had been treated at the outpatient clinic of the Diabetes Center in Yokohama Rosai hospital without admission. After 3 - month administration, the mean HbA1c value was significantly decreased (from 8.61 to 8.04%), and the mean body weight was also significantly reduced (from 71.0 to 69.2 kg). However, there were marked individual differences in the effects. We compared background factors between groups with and without improvement. The results showed that liraglutide was particularly effective in patients with a short duration of diabetes in whom endogenous insulin secretion, which was evaluated by examining fasting C-peptide with fasting sugar level, was well maintained. Furthermore, we examined the characteristics of eating behavior before and after administration using a questionnaire. In patients with a significant decrease in the blood sugar level, there was a marked improvement in the eating behavior pattern. Therefore, not only a decrease in the blood sugar level related to improved ability of endogenous insulin secretion but also the improvement of a patient